Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.

Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.

<h4>Objective</h4>Mitochondrial oxidative stress is the basis for pancreatic β-cell apoptosis and a common pathway for numerous types of damage, including glucotoxicity and lipotoxicity. We cultivated mice pancreatic β-cell tumor Min6 cell lines in vitro and observed pancreatic β-cell ap...

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Bibliographic Details
Main Authors: Zhen Li, Zhiguang Zhou, Gan Huang, Fang Hu, Yufei Xiang, Lining He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204601/?tool=EBI

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