Cardiomyocyte Hypocontractility and Reduced Myofibril Density in End-Stage Pediatric Cardiomyopathy

Cardiomyocyte Hypocontractility and Reduced Myofibril Density in End-Stage Pediatric Cardiomyopathy

Dilated cardiomyopathy amongst children (pediatric cardiomyopathy, pediatric CM) is associated with a high morbidity and mortality. Because little is known about the pathophysiology of pediatric CM, treatment is largely based on adult heart failure therapy. The reason for high morbidity and mortalit...

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Bibliographic Details
Main Authors: Ilse A. E. Bollen, Marijke van der Meulen, Kyra de Goede, Diederik W. D. Kuster, Michiel Dalinghaus, Jolanda van der Velden
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Physiology
Subjects:
pediatrics
heart failure
titin
myofibril density
hypocontractility
cardiomyopathy
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2017.01103/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2017.01103/full

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