Analysis of compliance dynamics in patients with chronic obstructive pulmonary disease on the background of vaccination against pneumococcal infection

• Main Authors: G L Jgnatova, V N Antonov
• Format: Article
• Language: Russian
• Published: "Consilium Medicum" Publishing house 2018-03-01
• Series: Терапевтический архив
• Subjects: copd; vaccine prophylaxis; compliance
• Online Access: https://ter-arkhiv.ru/0040-3660/article/viewFile/32734/pdf
• ISSN: 0040-3660; 2309-5342

Aim. The analysis of the dynamics of compliance in patients with chronic obstructive pulmonary disease (COPD) on a background of vaccination. Material and Methods. A total of 394 male patients are covered by this study. The main endpoints of observation are as follows: 1. To evaluate the effectiveness It’s important the dynamics of scores for mMRC, FEV1, the number of exacerbations, hospitalizations, the number of pneumonia cases. 2. To assess compliance it’s necessary to conduct a test for adherence to the Moriska-Green questionnaire. For vaccine prophylaxis, 13-valent conjugated pneumococcal vaccine Prevenar-13 and a 23-valent polysaccharide vaccine Pnevmo23 were used. The dynamics of changes in the parameters studied was evaluated within 4 years of the therapy initiation. Results. The inclusion of vaccine prophylaxis of PCV13 in the patient management plan allows to reduce a degree of dyspnea and stabilize the main functional parameters of the respiratory system not only in the short term, but also for at least next 4 years. PCV13 vaccination of can be considered as a basic therapy along with bronchodilator therapy. The use of vaccine prophylaxis PCV13 significantly increases the compliance and adherence of patients to a therapy. Conclusions. The use of vaccine prophylaxis PKV13 significantly increases patients ' compliance and adherence to the therapy.