Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer

Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer

Abstract Background miR-182-5p (miR-182) is an oncogenic microRNA (miRNA) found in different tumor types and one of the most up-regulated miRNA in colorectal cancer (CRC). Although this microRNA is expressed in the early steps of tumor development, its role in driving tumorigenesis is unclear. Metho...

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Bibliographic Details
Main Authors: Lisa Perilli, Sofia Tessarollo, Laura Albertoni, Matteo Curtarello, Anna Pastò, Efrem Brunetti, Matteo Fassan, Massimo Rugge, Stefano Indraccolo, Alberto Amadori, Stefania Bortoluzzi, Paola Zanovello
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Colorectal cancer
microRNA
Apoptosis
Cell proliferation
Tumorigenesis
Online Access:http://link.springer.com/article/10.1186/s12885-019-5982-9

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