Contribution of Bone Morphogenetic Protein-2 to Aortic Valve Calcification in Aged Rat

Contribution of Bone Morphogenetic Protein-2 to Aortic Valve Calcification in Aged Rat

Although aging is well established as an important risk factor for aortic stenosis, the mechanism of age-related aortic valve calcification is yet unknown. Here, we investigated this mechanism in tissue and cellular levels using middle-aged rats. Aortic valve specimens were obtained by dissecting fr...

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Bibliographic Details
Main Authors:	Kazuhiko Seya, Zaiqiang Yu, Kouta Kanemaru, Kazuyuki Daitoku, Yui Akemoto, Hiroyuki Shibuya, Ikuo Fukuda, Ken Okumura, Shigeru Motomura, Ken-Ichi Furukawa
Format:	Article
Language:	English
Published:	Elsevier 2011-01-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861319307947

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