Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4

Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4

<p>Abstract</p> <p>Background</p> <p>Apoptosis is an early event involved in cardiomyopathy associated with diabetes mellitus. Toll-like receptor (TLR) signaling triggers cell apoptosis through multiple mechanisms. Up-regulation of TLR4 expression has been shown in diab...

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Bibliographic Details
Main Authors:	Singh Manpreet, Shunnar Aminah, Lai Xiaoyan, Cheng Xiaoshu, Jiang Nan, Zhang Xusheng, Zheng Xiufen, Zhu Huaqing, Peng Tianqing, Zhang Yuwei, Riordan Neil, Bogin Vladimir, Tong Nanwei, Min Wei-Ping
Format:	Article
Language:	English
Published:	BMC 2010-12-01
Series:	Journal of Translational Medicine
Online Access:	http://www.translational-medicine.com/content/8/1/133

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