Low Doses of Silver Nanoparticles Selectively Induce Lipid Peroxidation and Proteotoxic Stress in Mesenchymal Subtypes of Triple-Negative Breast Cancer

Low Doses of Silver Nanoparticles Selectively Induce Lipid Peroxidation and Proteotoxic Stress in Mesenchymal Subtypes of Triple-Negative Breast Cancer

Molecular profiling of tumors shows that triple-negative breast cancer (TNBC) can be stratified into mesenchymal (claudin-low breast cancer; CLBC) and epithelial subtypes (basal-like breast cancer; BLBC). Subtypes differ in underlying genetics and in response to therapeutics. Several reports indicat...

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Bibliographic Details
Main Authors: Christina M. Snyder, Monica M. Rohde, Cale D. Fahrenholtz, Jessica Swanner, John Sloop, George L. Donati, Cristina M. Furdui, Ravi Singh
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
silver nanoparticle
triple-negative breast cancer
proteotoxic stress
lipid peroxidation
precision medicine
nanomedicine
Online Access:https://www.mdpi.com/2072-6694/13/16/4217

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