The Metabolic Inhibition Model Which Predicts the Intestinal Absorbability and Metabolizability of Drug: Theory and Experiment

<p>The intestinal absorption of analgesic peptides (leucine enkephalin and kyotorphin) and modified peptides in rat were studied. Although these peptides were not absorbed, the absorbability (absorption clearance) of these peptides were increased in the presence of peptidase inhibitors. In ord...

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Bibliographic Details
Main Authors: Mizuma Takashi, Awazu Shoji
Format: Article
Language:English
Published: BMC 1998-01-01
Series:Biological Procedures Online
Subjects:
Online Access:http://www.biologicalprocedures.com/bpo/arts/1/8/m8.htm