Simulations of blood as a suspension predicts a depth dependent hematocrit in the circulation throughout the cerebral cortex.

Simulations of blood as a suspension predicts a depth dependent hematocrit in the circulation throughout the cerebral cortex.

Recent advances in modeling oxygen supply to cortical brain tissue have begun to elucidate the functional mechanisms of neurovascular coupling. While the principal mechanisms of blood flow regulation after neuronal firing are generally known, mechanistic hemodynamic simulations cannot yet pinpoint t...

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Bibliographic Details
Main Authors: Grant Hartung, Claudia Vesel, Ryan Morley, Ali Alaraj, John Sled, David Kleinfeld, Andreas Linninger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006549

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