New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5<i>H</i>)ones as Possible Anti-Inflammatory Agents

New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5<i>H</i>)ones as Possible Anti-Inflammatory Agents

Background: Inflammation is a complex response to noxious stimuli promoted by the release of chemical mediators from the damaged cells. Metabolic products of arachidonic acid, produced by the action of cyclooxygenase and lipoxygenase, play important roles in this process. Several non-steroidal anti-...

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Bibliographic Details
Main Authors: Christophe Tratrat, Michelyne Haroun, Aliki Paparisva, Charalmpos Kamoutsis, Anthi Petrou, Antonis Gavalas, Phaedra Eleftheriou, Athina Geronikaki, Katharigatta N. Venugopala, Hafedh Kochkar, Anroop B. Nair
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
anti-inflammatory
thiazole
triazole
COX
LOX
docking
Online Access:https://www.mdpi.com/1420-3049/26/3/659

Internet

https://www.mdpi.com/1420-3049/26/3/659

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