Positive allosteric modulation of TRPV1 as a novel analgesic mechanism

Positive allosteric modulation of TRPV1 as a novel analgesic mechanism

<p>Abstract</p> <p>Background</p> <p>The prevalence of long-term opiate use in treating chronic non-cancer pain is increasing, and prescription opioid abuse and dependence are a major public health concern. To explore alternatives to opioid-based analgesia, the present...

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Bibliographic Details
Main Authors: Lebovitz Evan E, Keller Jason M, Kominsky Hal, Kaszas Krisztian, Maric Dragan, Iadarola Michael J
Format: Article
Language:English
Published: SAGE Publishing 2012-09-01
Series:Molecular Pain
Subjects:
TRPV1
Pain
Capsaicin
Vanilloid
Nociception
Resiniferatoxin
ATF3
Dorsal root ganglion
MRS1477
Adelta fiber
Online Access:http://www.molecularpain.com/content/8/1/70

Internet

http://www.molecularpain.com/content/8/1/70

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