Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes.

Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes.

BACKGROUND:Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk variants, common in populations with recent African ancestry, are strongly associated with non-diabetic nephropathy, end-stage kidney disease, and shorter allograft survival in deceased-donor kidneys (autosomal recessive inheritance). Ci...

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Main Authors: Casey R Dorr, Barry I Freedman, Pamela J Hicks, W Mark Brown, Gregory B Russell, Bruce A Julian, Stephen O Pastan, Michael D Gautreaux, Amutha Muthusamy, Srinath Chinnakotla, Vera Hauptfeld, Robert A Bray, Allan D Kirk, Jasmin Divers, Ajay K Israni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4824450?pdf=render

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