The negative elongation factor NELF promotes induced transcriptional response of Drosophila ecdysone-dependent genes

Abstract For many years it was believed that promoter-proximal RNA-polymerase II (Pol II) pausing manages the transcription of genes in Drosophila development by controlling spatiotemporal properties of their activation and repression. But the exact proteins that cooperate to stall Pol II in promote...

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Bibliographic Details
Main Authors: Marina Yu. Mazina, Elena V. Kovalenko, Nadezhda E. Vorobyeva
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80650-1