A theoretical justification for single molecule peptide sequencing.

The proteomes of cells, tissues, and organisms reflect active cellular processes and change continuously in response to intracellular and extracellular cues. Deep, quantitative profiling of the proteome, especially if combined with mRNA and metabolite measurements, should provide an unprecedented vi...

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Bibliographic Details
Main Authors: Jagannath Swaminathan, Alexander A Boulgakov, Edward M Marcotte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004080