Deoxynivalenol Impairs Porcine Intestinal Host Defense Peptide Expression in Weaned Piglets and IPEC-J2 Cells

Deoxynivalenol Impairs Porcine Intestinal Host Defense Peptide Expression in Weaned Piglets and IPEC-J2 Cells

Host defense peptides (HDPs) are efficient defense components of the innate immune system, playing critical roles in intestinal homeostasis and protection against pathogens. This study aims to investigate the interference effects of DON on the intestinal porcine HDPs expression in piglets and intest...

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Bibliographic Details
Main Authors: Shuai Wang, Jiacheng Yang, Beiyu Zhang, Kuntan Wu, Ao Yang, Chong Li, Jiacai Zhang, Cong Zhang, Shahid Ali Rajput, Niya Zhang, Lvhui Sun, Desheng Qi
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Toxins
Subjects:
Deoxynivalenol
Weaned piglets
Host defense peptides
NOD2
Caspase-12
Online Access:https://www.mdpi.com/2072-6651/10/12/541

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