Bone cements for percutaneous vertebroplasty and balloon kyphoplasty: Current status and future developments

• Main Authors: Zhiwei He, Qingpan Zhai, Muli Hu, Chengbin Cao, Jihui Wang, Huilin Yang, Bin Li
• Format: Article
• Language: English
• Published: Elsevier 2015-01-01
• Series: Journal of Orthopaedic Translation
• Subjects: balloon kyphoplasty; bone cement; filling materials; osteoporotic vertebral compression fractures; vertebroplasty
• Online Access: http://www.sciencedirect.com/science/article/pii/S2214031X14002551

Osteoporotic vertebral compression fractures (OVCFs) have gradually evolved into a serious health care problem globally. In order to reduce the morbidity of OVCF patients and improve their life quality, two minimally invasive surgery procedures, vertebroplasty (VP) and balloon kyphoplasty (BKP), have been developed. Both VP and BKP require the injection of bone cement into the vertebrae of patients to stabilize fractured vertebra. As such, bone cement as the filling material plays an essential role in the effectiveness of these treatments. In this review article, we summarize the bone cements that are currently available in the market and those still under development. Two major categories of bone cements, nondegradable acrylic bone cements (ABCs) and degradable calcium phosphate cements (CPCs), are introduced in detail. We also provide our perspectives on the future development of bone cements for VP and BKP.