Understanding the Pathogenesis of Angelman Syndrome through Animal Models

Angelman syndrome (AS) is a neurodevelopmental disorder characterized by severe mental retardation, lack of speech, ataxia, susceptibility to seizures, and unique behavioral features such as easily provoked smiling and laughter and autistic features. The disease is primarily caused by deletion or lo...

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Bibliographic Details
Main Author: Nihar Ranjan Jana
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2012/710943