Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives

<abstract language="eng">The sesquiterpene (+)-allo-aromadendrane-10b-14-diol 1 was the lead compound to the preparation of several derivatives in order to test their biological activity against A. salina, C. sphaerospermum, E. coli and S. aureus. In this way the monoalcohols (+)-vir...

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Main Authors:	Dênis Pires de Lima, Adilson Beatriz, Alexandre Ayoroa Ramos, João Máximo de Siqueira, Celso Corrêa de Oliveira, Maria Rita Marques
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Química 1997-12-01
Series:	Química Nova
Subjects:	allo-aromadendrane-10b -14-diol D. glabriuscula biological activity
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421997000600008

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spelling	doaj-17810a2cdaf6437385e8052a08951b9e2020-11-24T22:26:12ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70641997-12-0120661662010.1590/S0100-40421997000600008Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivativesDênis Pires de LimaAdilson BeatrizAlexandre Ayoroa RamosJoão Máximo de SiqueiraCelso Corrêa de OliveiraMaria Rita Marques<abstract language="eng">The sesquiterpene (+)-allo-aromadendrane-10b-14-diol 1 was the lead compound to the preparation of several derivatives in order to test their biological activity against A. salina, C. sphaerospermum, E. coli and S. aureus. In this way the monoalcohols (+)-viridiflorol 4, 9 and 11 were synthesized from 1 together with the acetal 6, the ketal 7, and the ketone 8. The oxirane 3 and nitrile 5 were also prepared using as an intermediate the tosylate derivative 2.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421997000600008allo-aromadendrane-10b -14-diolD. glabriusculabiological activity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Dênis Pires de Lima Adilson Beatriz Alexandre Ayoroa Ramos João Máximo de Siqueira Celso Corrêa de Oliveira Maria Rita Marques
spellingShingle	Dênis Pires de Lima Adilson Beatriz Alexandre Ayoroa Ramos João Máximo de Siqueira Celso Corrêa de Oliveira Maria Rita Marques Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives Química Nova allo-aromadendrane-10b -14-diol D. glabriuscula biological activity
author_facet	Dênis Pires de Lima Adilson Beatriz Alexandre Ayoroa Ramos João Máximo de Siqueira Celso Corrêa de Oliveira Maria Rita Marques
author_sort	Dênis Pires de Lima
title	Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives
title_short	Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives
title_full	Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives
title_fullStr	Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives
title_full_unstemmed	Transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos Chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives
title_sort	transformações químicas do (+)-10b,14-diol-allo-aromadendrano, isolado de duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) e avaliações biológicas de alguns derivados obtidos chemical modifications of (+)-allo-aromadendrane-10b,14-diol isolated from duguetia glabriuscula r. e. fries (r. e. fries) (annonaceae) and biological evaluation of some obtained derivatives
publisher	Sociedade Brasileira de Química
series	Química Nova
issn	0100-4042 1678-7064
publishDate	1997-12-01
description	<abstract language="eng">The sesquiterpene (+)-allo-aromadendrane-10b-14-diol 1 was the lead compound to the preparation of several derivatives in order to test their biological activity against A. salina, C. sphaerospermum, E. coli and S. aureus. In this way the monoalcohols (+)-viridiflorol 4, 9 and 11 were synthesized from 1 together with the acetal 6, the ketal 7, and the ketone 8. The oxirane 3 and nitrile 5 were also prepared using as an intermediate the tosylate derivative 2.
topic	allo-aromadendrane-10b -14-diol D. glabriuscula biological activity
url	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421997000600008
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