Data-Driven Information Extraction from Chinese Electronic Medical Records.

This study aims to propose a data-driven framework that takes unstructured free text narratives in Chinese Electronic Medical Records (EMRs) as input and converts them into structured time-event-description triples, where the description is either an elaboration or an outcome of the medical event.Ou...

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Main Authors: Dong Xu, Meizhuo Zhang, Tianwan Zhao, Chen Ge, Weiguo Gao, Jia Wei, Kenny Q Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4546596?pdf=render
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spelling doaj-177a747b2d9949d297438e194bc2c95a2020-11-25T00:57:16ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01108e013627010.1371/journal.pone.0136270Data-Driven Information Extraction from Chinese Electronic Medical Records.Dong XuMeizhuo ZhangTianwan ZhaoChen GeWeiguo GaoJia WeiKenny Q ZhuThis study aims to propose a data-driven framework that takes unstructured free text narratives in Chinese Electronic Medical Records (EMRs) as input and converts them into structured time-event-description triples, where the description is either an elaboration or an outcome of the medical event.Our framework uses a hybrid approach. It consists of constructing cross-domain core medical lexica, an unsupervised, iterative algorithm to accrue more accurate terms into the lexica, rules to address Chinese writing conventions and temporal descriptors, and a Support Vector Machine (SVM) algorithm that innovatively utilizes Normalized Google Distance (NGD) to estimate the correlation between medical events and their descriptions.The effectiveness of the framework was demonstrated with a dataset of 24,817 de-identified Chinese EMRs. The cross-domain medical lexica were capable of recognizing terms with an F1-score of 0.896. 98.5% of recorded medical events were linked to temporal descriptors. The NGD SVM description-event matching achieved an F1-score of 0.874. The end-to-end time-event-description extraction of our framework achieved an F1-score of 0.846.In terms of named entity recognition, the proposed framework outperforms state-of-the-art supervised learning algorithms (F1-score: 0.896 vs. 0.886). In event-description association, the NGD SVM is superior to SVM using only local context and semantic features (F1-score: 0.874 vs. 0.838).The framework is data-driven, weakly supervised, and robust against the variations and noises that tend to occur in a large corpus. It addresses Chinese medical writing conventions and variations in writing styles through patterns used for discovering new terms and rules for updating the lexica.http://europepmc.org/articles/PMC4546596?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Dong Xu
Meizhuo Zhang
Tianwan Zhao
Chen Ge
Weiguo Gao
Jia Wei
Kenny Q Zhu
spellingShingle Dong Xu
Meizhuo Zhang
Tianwan Zhao
Chen Ge
Weiguo Gao
Jia Wei
Kenny Q Zhu
Data-Driven Information Extraction from Chinese Electronic Medical Records.
PLoS ONE
author_facet Dong Xu
Meizhuo Zhang
Tianwan Zhao
Chen Ge
Weiguo Gao
Jia Wei
Kenny Q Zhu
author_sort Dong Xu
title Data-Driven Information Extraction from Chinese Electronic Medical Records.
title_short Data-Driven Information Extraction from Chinese Electronic Medical Records.
title_full Data-Driven Information Extraction from Chinese Electronic Medical Records.
title_fullStr Data-Driven Information Extraction from Chinese Electronic Medical Records.
title_full_unstemmed Data-Driven Information Extraction from Chinese Electronic Medical Records.
title_sort data-driven information extraction from chinese electronic medical records.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2015-01-01
description This study aims to propose a data-driven framework that takes unstructured free text narratives in Chinese Electronic Medical Records (EMRs) as input and converts them into structured time-event-description triples, where the description is either an elaboration or an outcome of the medical event.Our framework uses a hybrid approach. It consists of constructing cross-domain core medical lexica, an unsupervised, iterative algorithm to accrue more accurate terms into the lexica, rules to address Chinese writing conventions and temporal descriptors, and a Support Vector Machine (SVM) algorithm that innovatively utilizes Normalized Google Distance (NGD) to estimate the correlation between medical events and their descriptions.The effectiveness of the framework was demonstrated with a dataset of 24,817 de-identified Chinese EMRs. The cross-domain medical lexica were capable of recognizing terms with an F1-score of 0.896. 98.5% of recorded medical events were linked to temporal descriptors. The NGD SVM description-event matching achieved an F1-score of 0.874. The end-to-end time-event-description extraction of our framework achieved an F1-score of 0.846.In terms of named entity recognition, the proposed framework outperforms state-of-the-art supervised learning algorithms (F1-score: 0.896 vs. 0.886). In event-description association, the NGD SVM is superior to SVM using only local context and semantic features (F1-score: 0.874 vs. 0.838).The framework is data-driven, weakly supervised, and robust against the variations and noises that tend to occur in a large corpus. It addresses Chinese medical writing conventions and variations in writing styles through patterns used for discovering new terms and rules for updating the lexica.
url http://europepmc.org/articles/PMC4546596?pdf=render
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