Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma.

Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma.

Aerobic glycolysis and mitochondrial dysfunction are common features of aggressive cancer growth. We observed promoter methylation and loss of expression in neurofilament heavy polypeptide (NEFH) in a significant proportion of primary esophageal squamous cell carcinoma (ESCC) samples that were of a...

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Bibliographic Details
Main Authors: Myoung Sook Kim, Xiaofei Chang, Cynthia LeBron, Jatin K Nagpal, Juna Lee, Yiping Huang, Keishi Yamashita, Barry Trink, Edward A Ratovitski, David Sidransky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2815775?pdf=render

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http://europepmc.org/articles/PMC2815775?pdf=render

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