Antioxidants and Quality of Aging: Further Evidences for a Major Role of TXNRD1 Gene Variability on Physical Performance at Old Age

Antioxidants and Quality of Aging: Further Evidences for a Major Role of TXNRD1 Gene Variability on Physical Performance at Old Age

Oxidative stress is a major determinant of human aging and common hallmark of age-related diseases. A protective role against free radicals accumulation was shown for thioredoxin reductase TrxR1, a key antioxidant selenoprotein. The variability of encoding gene (TXNRD1) was previously found associat...

Full description

Bibliographic Details
Main Authors:	Serena Dato, Francesco De Rango, Paolina Crocco, Giuseppe Passarino, Giuseppina Rose
Format:	Article
Language:	English
Published:	Hindawi Limited 2015-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2015/926067

Similar Items

Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity
by: Giuseppe Passarino, et al.
Published: (2013-08-01)

Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity.
by: Giuseppina Rose, et al.
Published: (2011-01-01)

Inter-Individual Variability in Xenobiotic-Metabolizing Enzymes: Implications for Human Aging and Longevity
by: Paolina Crocco, et al.
Published: (2019-05-01)

Inositol Polyphosphate Multikinase (<i>IPMK</i>), a Gene Coding for a Potential Moonlighting Protein, Contributes to Human Female Longevity
by: Francesco De Rango, et al.
Published: (2019-02-01)

Bitter taste receptor polymorphisms and human aging.
by: Daniele Campa, et al.
Published: (2012-01-01)

Epidemiological, genetic and epigenetic aspects of the research on healthy ageing and longevity
by: Montesanto Alberto, et al.
Published: (2012-04-01)

Omics in a Digital World: The Role of Bioinformatics in Providing New Insights Into Human Aging
by: Serena Dato, et al.
Published: (2021-06-01)

Expression Patterns of Muscle-Specific miR-133b and miR-206 Correlate with Nutritional Status and Sarcopenia
by: Francesca Iannone, et al.
Published: (2020-01-01)

Somatic point mutations in mtDNA control region are influenced by genetic background and associated with healthy aging: a GEHA study.
by: Giuseppina Rose, et al.
Published: (2010-10-01)

TXNRD1 Is an Unfavorable Prognostic Factor for Patients with Hepatocellular Carcinoma
by: Binsheng Fu, et al.
Published: (2017-01-01)

Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes.
by: Elena S Suvorova, et al.
Published: (2009-07-01)

Up-regulation of antioxidative proteins TRX1, TXNL1 and TXNRD1 in the cortex of PTZ kindling seizure model mice.
by: Jia-Tian Yu, et al.
Published: (2019-01-01)

Aging and Longevity between Genetic Background and Lifestyle Intervention
by: Giuseppe Passarino, et al.
Published: (2014-01-01)

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone
by: Laura Torrente, et al.
Published: (2020-02-01)

Multi-Tissue DNA Methylation Remodeling at Mitochondrial Quality Control Genes According to Diet in Rat Aging Models
by: Patrizia D’Aquila, et al.
Published: (2020-02-01)

Erratum: Multi-Tissue DNA Methylation Remodeling at Mitochondrial Quality Control Genes According to Diet in Rat Aging Models
by: Patrizia D’Aquila, et al.
Published: (2020-05-01)

Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo
by: Xiaoxia Liu, et al.
Published: (2020-09-01)

Circ0120816 acts as an oncogene of esophageal squamous cell carcinoma by inhibiting miR-1305 and releasing TXNRD1
by: Xiaoyong Li, et al.
Published: (2020-10-01)

Intraindividual variability, gait and falls in old age
by: Graveson, Jack
Published: (2017)

Lack of Association Between Polymorphisms in TXNRD2 and LMX1B and Primary Open-Angle Glaucoma in a Saudi Cohort
by: Altaf A. Kondkar, et al.
Published: (2021-08-01)

PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway
by: Lin Tuo, et al.
Published: (2018-12-01)

miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1
by: Shengni Hua, et al.
Published: (2019-07-01)

Further evidence of accelerated aging in bipolar disorder: Focus on GDF-15
by: Yang Fang, et al.
Published: (2018-03-01)

Untangling the Genetics of Human Longevity—A Challenging Quest
by: Serena Dato, et al.
Published: (2019-07-01)

Old Age and Aging in China
by: Lien-Tan Pan
Published: (2017-05-01)

The Golden Age of Cataclysmic Variables and Related Objects (Old and News)
by: F. Giovannelli, et al.
Published: (2015-02-01)

Education on Old Age and Ageing in School: An Analysis of Students’ Conceptions of Old Age and Ageing and Implications for Teaching
by: Franziska Ginschel, et al.
Published: (2020-10-01)

Old Age in the Old Times
by: Özge Bozkurtoğlu Özcan
Published: (2018-12-01)

Further experimental evidence that condensation is a major cause of airflow
by: Peter Paul Bunyard, et al.
Published: (2019-04-01)

Acceptance and perceptions of old age and aging
by: Mateja Lorber
Published: (2019-09-01)

What Is the Onset Age of Human Aging and Old Age?
by: Víctor Manuel Mendoza-Núñez, et al.
Published: (2016-03-01)

Effects of antioxidant supplementation on the aging process
by: Domenico Fusco, et al.
Published: (2007-10-01)

Old age known and unknown – chosen reflections on contemporary old age
by: Elżbieta Dubas
Published: (2014-05-01)

Transgender, aging and old age - Do transgender people get old?
by: Pedro Paulo Sammarco Antunes, et al.
Published: (2013-12-01)

Halon-1301 – further evidence of its performance as an age tracer in New Zealand groundwater
by: M. Beyer, et al.
Published: (2017-08-01)

Ageing Assessment and Management at Major-Hazard Industries
by: Francesca Milazzo Maria, et al.
Published: (2018-09-01)

Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host
by: Patrizia D’Aquila, et al.
Published: (2020-02-01)

Attitudes to old age and ageing in medieval society
by: Cummins, Josephine M.
Published: (2000)

"Is old age stigma? Ageing identity in Lithuania"
by: Rapolienė, Grazina
Published: (2012)

mTOR and Aging: An Old Fashioned Dress
by: Giovanni Stallone, et al.
Published: (2019-06-01)

Cannot write session to /tmp/vufind_sessions/sess_rs0ofa7nrvub53ltolq2pub3kh