OSTEOARTHRITIS: CURRENT CLINICAL CONCEPT AND SOME PROMISING THERAPEUTIC APPROACHES

In recent years, there has been a trend toward changing the clinical concept of osteoarthritis (OA). This disease has been considered as an age-related disease and the long-term result of a current pathological process for a very long time. However, many experts are now inclined to consider it neces...

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Bibliographic Details
Main Authors: A. E. Karateev, A. M. Lila
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2018-03-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/2502
Description
Summary:In recent years, there has been a trend toward changing the clinical concept of osteoarthritis (OA). This disease has been considered as an age-related disease and the long-term result of a current pathological process for a very long time. However, many experts are now inclined to consider it necessary to identify the early, pre-X-ray stage of OA, when adequate treatment may not only halt the progression, but also achieve the regression of joint structural changes. This review deals with a number of pathogenetic and clinical aspects of the early stages of OA, which are important for timely diagnosis and pathogenetic therapy choice. It also considers some therapeutic approaches, both a "classic" and recently actively discussed methods for using platelet-rich plasma and autologous chondrocyte transplantation.
ISSN:1995-4484
1995-4492