Synthesis of 1-isopropyl-3-acyl-5-methyl-benzimidazolone Derivatives and Their Antimicrobial Activity

Synthesis of 1-isopropyl-3-acyl-5-methyl-benzimidazolone Derivatives and Their Antimicrobial Activity

A series of N-acylated analogues of 1-isopropyl-3-acyl-5-methyl-benzimidazolone were synthesized. Bioassay results indicated that analogues 5-07 and 5-19 exhibited the most potency against Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. Analogu...

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Bibliographic Details
Main Authors: Shaopeng Wei, Xinqi Gan, Chunnan Yang, Nan Xu, Zhiqin Ji
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:International Journal of Molecular Sciences
Subjects:
5-methyl-benzimidazolone
N-acylated derivatives
antimicrobial activity
Online Access:http://www.mdpi.com/1422-0067/14/4/6790

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