Microglial Morphology Across Distantly Related Species: Phylogenetic, Environmental and Age Influences on Microglia Reactivity and Surveillance States

Microglial Morphology Across Distantly Related Species: Phylogenetic, Environmental and Age Influences on Microglia Reactivity and Surveillance States

Microglial immunosurveillance of the brain parenchyma to detect local perturbations in homeostasis, in all species, results in the adoption of a spectrum of morphological changes that reflect functional adaptations. Here, we review the contribution of these changes in microglia morphology in distant...

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Main Authors: Dario Carvalho-Paulo, João Bento Torres Neto, Carlos Santos Filho, Thais Cristina Galdino de Oliveira, Aline Andrade de Sousa, Renata Rodrigues dos Reis, Zaire Alves dos Santos, Camila Mendes de Lima, Marcus Augusto de Oliveira, Nivin Mazen Said, Sinara Franco Freitas, Marcia Consentino Kronka Sosthenes, Giovanni Freitas Gomes, Ediely Pereira Henrique, Patrick Douglas Côrrea Pereira, Lucas Silva de Siqueira, Mauro André Damasceno de Melo, Cristovam Guerreiro Diniz, Nara Gyzely de Morais Magalhães, José Antonio Picanço Diniz, Pedro Fernando da Costa Vasconcelos, Daniel Guerreiro Diniz, Daniel Clive Anthony, David Francis Sherry, Dora Brites, Cristovam Wanderley Picanço Diniz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
age and environment influence on microglia alteration
brain size and microglia response cognitive performances
Felsenstein’s independent phylogenetic contrast
microglia
mouse
bat
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.683026/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.683026/full

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