DL-3-n-butylphthalide protects the blood-brain barrier against ischemia/hypoxia injury via upregulation of tight junction proteins

Abstract. Background:. The increased permeability of the blood-brain barrier (BBB) induced by ischemia/hypoxia is generally correlated with alteration of tight junctions (TJs). DL-3-n-butylphthalide (NBP) has been shown to exert neuroprotective effects after ischemic injury. However, few studies hav...

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Bibliographic Details
Main Authors: Zhan-Ying Ye, Han-Ying Xing, Bei Wang, Min Liu, Pei-Yuan Lv, Qiang Shi
Format: Article
Language:English
Published: Wolters Kluwer 2019-06-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000232