Clinical characteristics and prognosis in patients with hyponatremic encephalopathy

• Main Authors: Jorge Cestari, Ariel Leston Taburet, Conrado Struck, Guillermo Alemano
• Format: Article
• Language: Spanish
• Published: Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires 2015-01-01
• Series: Revista de Nefrología, Diálisis y Trasplante
• Subjects: hiponatremia; encefalopatías; morbilidad; encefalopatía hiponatrémica; secuelas neurológicas; Charlson Score
• Online Access: http://www.revistarenal.org.ar/index.php/rndt/article/view/131

Introduction: Hyponatremic encephalopathy mortality rate reaches about 50% in some special groups of patients (pediatric, child-bearing age women, etc.). However, morbimortality seems to be much lower in men and elderly population. Methods: A retrospective and observational study on patients with hyponatremic encephalopathy diagnosis was carried out. Results: 47 patients with hyponatremic encephalopathy diagnosis were identified. It was an elderly population (age 69±15 years) with women prevalence. In-hospital mortality was 19.1% and neurological aftermaths in the survivors were 27%. Charlson score and delay to initiate treatment were associated to larger in-hospital mortality. Conclusion: mortality rate observed in our population is less than the one observed in other cohorts, probably due to the fact of being a low risk population. In a logistic regression model, delay in initiating an adequate treatment is associated to larger mortality rate in the studied population.