PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES

PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES

There were illustrated the main questions of development of new generation drug delivery systems as hybrid nanomaterials as follows: selection of nanocarrier, its standardization and the methods of immobilization of biologically active and medicinal substances. The basic organs of distribution and a...

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Main Authors: R. Y. Yakovlev, I. I. Kulakova, G. A. Badun, G. V. Lisichkin, A. V. Valueva, N. G. Selezenev, N. B. Leonidov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
drug delivery systems
detonation nanodiamond
nanocarrrier
carbon nanoparticles
immobilization drugs
hybrid nanomaterials
Online Access:https://www.pharmjournal.ru/jour/article/view/290
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spelling doaj-174c0101c6f947bf9d38b60a7820008b2021-07-28T13:06:54ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01036066290PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIESR. Y. Yakovlev0I. I. Kulakova1G. A. Badun2G. V. Lisichkin3A. V. Valueva4N. G. Selezenev5N. B. Leonidov6I.P. Pavlov Ryzan State Medical University; M.V. Lomonosov Moscow State UniversityM.V. Lomonosov Moscow State UniversityM.V. Lomonosov Moscow State UniversityM.V. Lomonosov Moscow State UniversityI.P. Pavlov Ryzan State Medical UniversityI.P. Pavlov Ryzan State Medical UniversityI.P. Pavlov Ryzan State Medical UniversityThere were illustrated the main questions of development of new generation drug delivery systems as hybrid nanomaterials as follows: selection of nanocarrier, its standardization and the methods of immobilization of biologically active and medicinal substances. The basic organs of distribution and accumulation of advanced carbon nanocarrier - detonation nanodiamond were identified. It was shown that antihypoxic effect of the nanodiamond-glycine conjugate increased in comparison with a native Glycine and Mexidolum® as reference drugs.https://www.pharmjournal.ru/jour/article/view/290drug delivery systemsdetonation nanodiamondnanocarrriercarbon nanoparticlesimmobilization drugshybrid nanomaterials
collection DOAJ
language Russian
format Article
sources DOAJ
author R. Y. Yakovlev
I. I. Kulakova
G. A. Badun
G. V. Lisichkin
A. V. Valueva
N. G. Selezenev
N. B. Leonidov
spellingShingle R. Y. Yakovlev
I. I. Kulakova
G. A. Badun
G. V. Lisichkin
A. V. Valueva
N. G. Selezenev
N. B. Leonidov
PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES
Разработка и регистрация лекарственных средств
drug delivery systems
detonation nanodiamond
nanocarrrier
carbon nanoparticles
immobilization drugs
hybrid nanomaterials
author_facet R. Y. Yakovlev
I. I. Kulakova
G. A. Badun
G. V. Lisichkin
A. V. Valueva
N. G. Selezenev
N. B. Leonidov
author_sort R. Y. Yakovlev
title PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES
title_short PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES
title_full PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES
title_fullStr PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES
title_full_unstemmed PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES
title_sort physical-chemical principles of the preparation of hybrid materials on the basis of detonation nanodiamonds as a new generation drug delivery systems and their properties
publisher LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
series Разработка и регистрация лекарственных средств
issn 2305-2066
2658-5049
publishDate 2019-01-01
description There were illustrated the main questions of development of new generation drug delivery systems as hybrid nanomaterials as follows: selection of nanocarrier, its standardization and the methods of immobilization of biologically active and medicinal substances. The basic organs of distribution and accumulation of advanced carbon nanocarrier - detonation nanodiamond were identified. It was shown that antihypoxic effect of the nanodiamond-glycine conjugate increased in comparison with a native Glycine and Mexidolum® as reference drugs.
topic drug delivery systems
detonation nanodiamond
nanocarrrier
carbon nanoparticles
immobilization drugs
hybrid nanomaterials
url https://www.pharmjournal.ru/jour/article/view/290
work_keys_str_mv AT ryyakovlev physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
AT iikulakova physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
AT gabadun physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
AT gvlisichkin physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
AT avvalueva physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
AT ngselezenev physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
AT nbleonidov physicalchemicalprinciplesofthepreparationofhybridmaterialsonthebasisofdetonationnanodiamondsasanewgenerationdrugdeliverysystemsandtheirproperties
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