PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES

PHYSICAL-CHEMICAL PRINCIPLES OF THE PREPARATION OF HYBRID MATERIALS ON THE BASIS OF DETONATION NANODIAMONDS AS A NEW GENERATION DRUG DELIVERY SYSTEMS AND THEIR PROPERTIES

There were illustrated the main questions of development of new generation drug delivery systems as hybrid nanomaterials as follows: selection of nanocarrier, its standardization and the methods of immobilization of biologically active and medicinal substances. The basic organs of distribution and a...

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Bibliographic Details
Main Authors: R. Y. Yakovlev, I. I. Kulakova, G. A. Badun, G. V. Lisichkin, A. V. Valueva, N. G. Selezenev, N. B. Leonidov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
drug delivery systems
detonation nanodiamond
nanocarrrier
carbon nanoparticles
immobilization drugs
hybrid nanomaterials
Online Access:https://www.pharmjournal.ru/jour/article/view/290
Description
Summary:There were illustrated the main questions of development of new generation drug delivery systems as hybrid nanomaterials as follows: selection of nanocarrier, its standardization and the methods of immobilization of biologically active and medicinal substances. The basic organs of distribution and accumulation of advanced carbon nanocarrier - detonation nanodiamond were identified. It was shown that antihypoxic effect of the nanodiamond-glycine conjugate increased in comparison with a native Glycine and Mexidolum® as reference drugs.
ISSN:2305-2066
2658-5049

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