Application and Comparison of Supervised Learning Strategies to Classify Polarity of Epithelial Cell Spheroids in 3D Culture

Application and Comparison of Supervised Learning Strategies to Classify Polarity of Epithelial Cell Spheroids in 3D Culture

Three-dimensional culture systems that allow generation of monolayered epithelial cell spheroids are widely used to study epithelial function in vitro. Epithelial spheroid formation is applied to address cellular consequences of (mono)-genetic disorders, that is, ciliopathies, in toxicity testing, o...

Full description

Bibliographic Details
Main Authors: Birga Soetje, Joachim Fuellekrug, Dieter Haffner, Wolfgang H. Ziegler
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
image analysis
epithelial morphogenesis
3D culture
polarity
spheroids
machine learning
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00248/full

Similar Items

Similar Items