In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1

In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1

Novel severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has claimed more than 3.3 million lives worldwide and still counting. As per the GISAID database, the genomics of SARS-CoV-2 has been extensively studied, with more than 500 genome submissions per day. Out of several hotspot mutation...

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Bibliographic Details
Main Authors: Armi Chaudhari, Minal Chaudhari, Sapna Mahera, Zuber Saiyed, Neelam M. Nathani, Shantanu Shukla, Dhaval Patel, Chirag Patel, Madhvi Joshi, Chaitanya G. Joshi
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Informatics in Medicine Unlocked
Subjects:
MADP1
hnRNP1
5′UTR
C241T
SARS-CoV-2
Protein-RNA complexes
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914821001556

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