Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.

Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.

The number of promising therapeutic interventions for Duchenne Muscular Dystrophy (DMD) is increasing rapidly. One of the proposed strategies is to use drugs that are known to act by multiple different mechanisms including inducing of homologous fetal form of adult genes, for example utrophin in pla...

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Main Authors: Alfredo D Guerron, Rashmi Rawat, Arpana Sali, Christopher F Spurney, Emidio Pistilli, Hee-Jae Cha, Gouri S Pandey, Ramkishore Gernapudi, Dwight Francia, Viken Farajian, Diana M Escolar, Laura Bossi, Magali Becker, Patricia Zerr, Sabine de la Porte, Heather Gordish-Dressman, Terence Partridge, Eric P Hoffman, Kanneboyina Nagaraju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2888587?pdf=render

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