Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress
Selenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb po...
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MDPI AG
2019-07-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/8/7/216 |
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doaj-1725a7c6024f4d4d9c4a21a08e49cffa2020-11-24T20:44:10ZengMDPI AGAntioxidants2076-39212019-07-018721610.3390/antiox8070216antiox8070216Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat StressIsidoros Seremelis0Georgios P. Danezis1Athanasios C. Pappas2Evangelos Zoidis3Kostas Fegeros4Chemistry Laboratory, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceChemistry Laboratory, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceDepartment of Nutritional Physiology and Feeding, Faculty of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, GreeceSelenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb poisoning and heat stress increase oxidation, mRNA levels of inflammatory proteins, and apoptotic proteins. Selenium seems to enhance the antioxidant status and alleviates these effects via upregulation of antioxidant proteins and other molecular effects. In this review, we analyze avian transcriptome key elements with particular emphasis on interactions with heavy metals and on relation to heat stress.https://www.mdpi.com/2076-3921/8/7/216Animal healthheat stressheavy metalsseleniumselenoproteinselenotranscriptome |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Isidoros Seremelis Georgios P. Danezis Athanasios C. Pappas Evangelos Zoidis Kostas Fegeros |
| spellingShingle |
Isidoros Seremelis Georgios P. Danezis Athanasios C. Pappas Evangelos Zoidis Kostas Fegeros Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress Antioxidants Animal health heat stress heavy metals selenium selenoprotein selenotranscriptome |
| author_facet |
Isidoros Seremelis Georgios P. Danezis Athanasios C. Pappas Evangelos Zoidis Kostas Fegeros |
| author_sort |
Isidoros Seremelis |
| title |
Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress |
| title_short |
Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress |
| title_full |
Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress |
| title_fullStr |
Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress |
| title_full_unstemmed |
Avian Stress-Related Transcriptome and Selenotranscriptome: Role during Exposure to Heavy Metals and Heat Stress |
| title_sort |
avian stress-related transcriptome and selenotranscriptome: role during exposure to heavy metals and heat stress |
| publisher |
MDPI AG |
| series |
Antioxidants |
| issn |
2076-3921 |
| publishDate |
2019-07-01 |
| description |
Selenium, through incorporation into selenoproteins, is one of the key elements of the antioxidant system. Over the past few years there has been increased interest in exploring those molecular mechanisms in chicken, responsible for the development of this protection system. In more detail, Cd/Pb poisoning and heat stress increase oxidation, mRNA levels of inflammatory proteins, and apoptotic proteins. Selenium seems to enhance the antioxidant status and alleviates these effects via upregulation of antioxidant proteins and other molecular effects. In this review, we analyze avian transcriptome key elements with particular emphasis on interactions with heavy metals and on relation to heat stress. |
| topic |
Animal health heat stress heavy metals selenium selenoprotein selenotranscriptome |
| url |
https://www.mdpi.com/2076-3921/8/7/216 |
| work_keys_str_mv |
AT isidorosseremelis avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT georgiospdanezis avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT athanasioscpappas avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT evangeloszoidis avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress AT kostasfegeros avianstressrelatedtranscriptomeandselenotranscriptomeroleduringexposuretoheavymetalsandheatstress |
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1716818198970499072 |