Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases

Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases

Rho-associated kinase (Rho-kinase/ROCK) was originally identified as an effector protein of the G protein Rho. Its involvement in various diseases, particularly cancer and cardiovascular disease, has been elucidated, and ROCK inhibitors have already been applied clinically for cerebral vasospasm and...

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Bibliographic Details
Main Authors:	Muneo Yamaguchi, Shintaro Nakao, Mitsuru Arima, Iori Wada, Yoshihiro Kaizu, Feng Hao, Shigeo Yoshida, Koh-hei Sonoda
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Journal of Ophthalmology
Online Access:	http://dx.doi.org/10.1155/2017/8543592

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