Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids

A survey was made on the incidence of Pneumocystis carinii in 361 rodents including sewer rats, albino rats, albino mice, guinea-pigs and rabbits. P. carinii was found in 4 of the 215 Rattus norvegicus examined (1,8%). These results accord with recent observations but disagree with investigations ma...

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Main Authors: Helly A. Lage, Suelena A. Lage
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1973-01-01
Series:Memórias do Instituto Oswaldo Cruz.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761973000100005
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spelling doaj-171670d32aa9423faca1e3181bbf9d912020-11-24T21:33:27ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80601973-01-01711-2879310.1590/S0074-02761973000100005Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroidsHelly A. LageSuelena A. LageA survey was made on the incidence of Pneumocystis carinii in 361 rodents including sewer rats, albino rats, albino mice, guinea-pigs and rabbits. P. carinii was found in 4 of the 215 Rattus norvegicus examined (1,8%). These results accord with recent observations but disagree with investigations made by the researchers who first studied this parasite in the past when high indexes of infection were found. However, in 20 albino rats treated with corticosteroids (betamethazone) we found 8 positive (40%) and in 20 albino mice treated by the same way, 9 were positive for P. carinii (45%). These results confirm the opportunistic character of P. carinii in rodents already well demonstrated in man.<br>Foi feita uma investigação sobre a ocorrência de P. carinii em 361 roedores, incluindo ratos de esgoto, ratos albinos, camundongos albinos, cobaios e coelhos. Só foram encontrados positivos 4 Rattus norvegicus em 215 examinados (1.8%). Estes resultados estão de acordo com observações feitas nos últimos anos, os quais constrastam com as verificações feitas nos primeiros anos, os quais contrastam com as verificações feitas nos primeiros anos de estudo do P. carinii, quando foram assinalados altos índices infecciosos. Entretanto, em 20 ratos albinos tratados com corticosteróides (betametasona) foram encontrados 8 positivos (40%); e em 20 camundongos albinos, tratados do mesmo modo, foram encontrados 9 positivos (45%). Estes resultados confirmaram o caráter oportunístico do P. carinii no roedores, do mesmo modo como acontece no homem.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761973000100005
collection DOAJ
language English
format Article
sources DOAJ
author Helly A. Lage
Suelena A. Lage
spellingShingle Helly A. Lage
Suelena A. Lage
Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
Memórias do Instituto Oswaldo Cruz.
author_facet Helly A. Lage
Suelena A. Lage
author_sort Helly A. Lage
title Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
title_short Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
title_full Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
title_fullStr Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
title_full_unstemmed Pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
title_sort pneumocystis carinii: its incidence in rodents and enhancement of the infection by corticosteroids
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 0074-0276
1678-8060
publishDate 1973-01-01
description A survey was made on the incidence of Pneumocystis carinii in 361 rodents including sewer rats, albino rats, albino mice, guinea-pigs and rabbits. P. carinii was found in 4 of the 215 Rattus norvegicus examined (1,8%). These results accord with recent observations but disagree with investigations made by the researchers who first studied this parasite in the past when high indexes of infection were found. However, in 20 albino rats treated with corticosteroids (betamethazone) we found 8 positive (40%) and in 20 albino mice treated by the same way, 9 were positive for P. carinii (45%). These results confirm the opportunistic character of P. carinii in rodents already well demonstrated in man.<br>Foi feita uma investigação sobre a ocorrência de P. carinii em 361 roedores, incluindo ratos de esgoto, ratos albinos, camundongos albinos, cobaios e coelhos. Só foram encontrados positivos 4 Rattus norvegicus em 215 examinados (1.8%). Estes resultados estão de acordo com observações feitas nos últimos anos, os quais constrastam com as verificações feitas nos primeiros anos, os quais contrastam com as verificações feitas nos primeiros anos de estudo do P. carinii, quando foram assinalados altos índices infecciosos. Entretanto, em 20 ratos albinos tratados com corticosteróides (betametasona) foram encontrados 8 positivos (40%); e em 20 camundongos albinos, tratados do mesmo modo, foram encontrados 9 positivos (45%). Estes resultados confirmaram o caráter oportunístico do P. carinii no roedores, do mesmo modo como acontece no homem.
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761973000100005
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