Genetic variability in <it>CYP3A4 </it>and <it>CYP3A5 </it>in primary liver, gastric and colorectal cancer patients

Genetic variability in <it>CYP3A4 </it>and <it>CYP3A5 </it>in primary liver, gastric and colorectal cancer patients

<p>Abstract</p> <p>Background</p> <p>Drug-metabolizing enzymes play a role in chemical carcinogenesis through enzymatic activation of procarcinogens to biologically reactive metabolites. The role of gene polymorphisms of several cytochrome P450 enzymes in digestive canc...

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Bibliographic Details
Main Authors: García Monserrat, Martínez Carmen, Sastre Javier, Pizarro Rosa, Ladero José M, García-Martín Elena, Gervasini Guillermo, Diaz-Rubio Manuel, Agúndez José AG
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/7/118

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