A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers
In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in ch...
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Elsevier
2019-11-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867019304611 |
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doaj-16e671a1a7584b529a88d932fd7bef582020-11-25T03:23:29ZengElsevierBrazilian Journal of Infectious Diseases1413-86702019-11-01236395409A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centersFabianne Carlesse0Liane Esteves Daudt1Adriana Seber2Álvaro Pimenta Dutra3Analy Salles de Azevedo Melo4Belinda Simões5Carla Renata Donato Macedo6Carmem Bonfim7Eliana Benites8Lauro Gregianin9Marjorie Vieira Batista10Marcelo Abramczyk11Vivian Tostes12Henrique Manoel Lederman13Maria Lúcia de Martino Lee14Sandra Loggetto15Cláudio Galvão de Castro Junior16Arnaldo Lopes Colombo17Instituto de Oncologia Pediátrica, UNIFESP, São Paulo, SP, Brazil; Universidade Federal de São Paulo, Escola Paulista de Medicina (EPM), UNIFESP, São Paulo, SP, BrazilUniversidade do Rio Grande do Sul, Hospital das Clínicas de Porto Alegre, Porto Alegre, RS, BrazilHospital Samaritano de São Paulo, São Paulo, SP, Brazil; ABHH, BrazilSanta Casa de Belo Horizonte, Belo Horizonte, MG, BrazilUniversidade Federal de São Paulo-UNIFESP, Laboratório Especial de Micologia (LEMI), São Paulo, SP, BrazilHospital das Clínicas de Ribeirão Preto-USP, São Paulo, SP, BrazilInstituto de Oncologia Pediátrica, UNIFESP, São Paulo, SP, BrazilHospital das Clínicas de Curitiba, Paraná, PR, BrazilGREENDAC, Jundiaí, São Paulo, BrazilHospital das Clínicas de Porto Alegre, Porto Alegre, RS, BrazilUniversidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, SP, BrazilHospital Infantil Darcy Vargas, Morumbi, SP, Brazil; Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Pediatria, São Paulo, SP, BrazilPro-Imagem medicina diagnóstica Ribeirão Preto, SP, BrazilInstituto de Oncologia Pediátrica, UNIFESP, São Paulo, SP, BrazilHospital Santa Marcelina TUCA, São Paulo, SP, Brazil; Hospital Israelita Albert Einstein, São Paulo, SP, BrazilHospital Infantil Sabará, São Paulo, SP, BrazilSanta Casa de Porto Alegre, Porto Alegre, RS, BrazilUniversidade Federal de São Paulo, Escola Paulista de Medicina, Disciplina de Infectologia, Brazil; Corresponding author.In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early diagnosis and best clinical management of IFDs are also presented. This document summarizes practical recommendations that will certainly help pediatricians to best treat their patients suffering of invasive fungal diseases. Keywords: Fungal infections, Children, Cancerhttp://www.sciencedirect.com/science/article/pii/S1413867019304611 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Fabianne Carlesse Liane Esteves Daudt Adriana Seber Álvaro Pimenta Dutra Analy Salles de Azevedo Melo Belinda Simões Carla Renata Donato Macedo Carmem Bonfim Eliana Benites Lauro Gregianin Marjorie Vieira Batista Marcelo Abramczyk Vivian Tostes Henrique Manoel Lederman Maria Lúcia de Martino Lee Sandra Loggetto Cláudio Galvão de Castro Junior Arnaldo Lopes Colombo |
| spellingShingle |
Fabianne Carlesse Liane Esteves Daudt Adriana Seber Álvaro Pimenta Dutra Analy Salles de Azevedo Melo Belinda Simões Carla Renata Donato Macedo Carmem Bonfim Eliana Benites Lauro Gregianin Marjorie Vieira Batista Marcelo Abramczyk Vivian Tostes Henrique Manoel Lederman Maria Lúcia de Martino Lee Sandra Loggetto Cláudio Galvão de Castro Junior Arnaldo Lopes Colombo A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers Brazilian Journal of Infectious Diseases |
| author_facet |
Fabianne Carlesse Liane Esteves Daudt Adriana Seber Álvaro Pimenta Dutra Analy Salles de Azevedo Melo Belinda Simões Carla Renata Donato Macedo Carmem Bonfim Eliana Benites Lauro Gregianin Marjorie Vieira Batista Marcelo Abramczyk Vivian Tostes Henrique Manoel Lederman Maria Lúcia de Martino Lee Sandra Loggetto Cláudio Galvão de Castro Junior Arnaldo Lopes Colombo |
| author_sort |
Fabianne Carlesse |
| title |
A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers |
| title_short |
A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers |
| title_full |
A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers |
| title_fullStr |
A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers |
| title_full_unstemmed |
A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers |
| title_sort |
consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in brazilian medical centers |
| publisher |
Elsevier |
| series |
Brazilian Journal of Infectious Diseases |
| issn |
1413-8670 |
| publishDate |
2019-11-01 |
| description |
In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early diagnosis and best clinical management of IFDs are also presented. This document summarizes practical recommendations that will certainly help pediatricians to best treat their patients suffering of invasive fungal diseases. Keywords: Fungal infections, Children, Cancer |
| url |
http://www.sciencedirect.com/science/article/pii/S1413867019304611 |
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