High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area

High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area

<p>Abstract</p> <p>Background</p> <p>This study was to evaluate the effect of excision repair cross-complementation group 1(ERCC1) expression on response to cisplatin-based induction chemotherapy (IC) followed by concurrent chemoradiation (CCRT) in locally advanced unre...

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Bibliographic Details
Main Authors: Chien Chih-Yen, Chen Chang-Han, Chiu Tai-Jan, Li Shau-Hsuan, Tsai Hsin-Ting, Chen Yi-Ju
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Journal of Translational Medicine
Subjects:
ERCC1, squamous cell carcinoma of head and neck, betel nuts, induction chemotherapy, chemoradiation
Online Access:http://www.translational-medicine.com/content/9/1/31

Internet

http://www.translational-medicine.com/content/9/1/31

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