DNA Methylation of Five Core Circadian Genes Jointly Contributes to Glucose Metabolism: A Gene-Set Analysis in Monozygotic Twins

DNA Methylation of Five Core Circadian Genes Jointly Contributes to Glucose Metabolism: A Gene-Set Analysis in Monozygotic Twins

The timing of daily fluctuations in blood glucose is tightly controlled by the circadian rhythm. DNA methylation accompanies the circadian clock, and aberrant DNA methylation has been associated with circadian disruption and hyperglycemia. However, the precise role of circadian genes methylation in...

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Bibliographic Details
Main Authors: Hao Peng, Yun Zhu, Jack Goldberg, Viola Vaccarino, Jinying Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
circadian rhythm
DNA methylation
monozygotic twins
glucose metabolism
epigenetics
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00329/full

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