Short-term erythropoietin treatment does not substantially modulate monocyte transcriptomes of patients with combined heart and renal failure.

Short-term erythropoietin treatment does not substantially modulate monocyte transcriptomes of patients with combined heart and renal failure.

Combined heart and renal failure is associated with high cardiovascular morbidity and mortality. Anti-oxidant and anti-inflammatory, non-hematopoietic effects of erythropoietin (EPO) treatment have been proposed. Monocytes may act as biosensors of the systemic environment. We hypothesized that monoc...

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Main Authors: Kim E Jie, Karien van der Putten, Sebastiaan Wesseling, Jaap A Joles, Marloes W Bergevoet, Floor Pepers-de Kort, Pieter A Doevendans, Yutaka Yasui, Qi Liu, Marianne C Verhaar, Carlo A Gaillard, Branko Braam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3434212?pdf=render

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