Inferring Active and Prognostic Ligand-Receptor Pairs with Interactions in Survival Regression Models

Modeling signal transduction in cancer cells has implications for targeting new therapies and inferring the mechanisms that improve or threaten a patient's treatment response. For transcriptome-wide studies, it has been proposed that simple correlation between a ligand and receptor pair implies...

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Bibliographic Details
Main Authors: Christina Ruggeri, Kevin H. Eng
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S16351