125I Seed Promotes Apoptosis in Non-small Lung Cancer Cells via the p38 MAPK-MDM2-p53 Signaling Pathway

125I Seed Promotes Apoptosis in Non-small Lung Cancer Cells via the p38 MAPK-MDM2-p53 Signaling Pathway

Purpose:125I seeds were effective in the treatment of non-small cell lung cancer in previous research. However, the exact signaling pathway-mediated apoptosis mechanism is still unclear. The present study analyzed the effects and potential mechanisms of 125I seed on the growth and migration of A549...

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Bibliographic Details
Main Authors: Tao Zhang, ZhiQiang Mo, Guangfeng Duan, Rijie Tang, Fujun Zhang, Mingjian Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
125I seed
non-small cell lung cancer
p38
p53
MDM2
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.582511/full

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