Eukaryotic Cell Toxicity and HSA Binding of [Ru(Me4phen)(bb7)]2+ and the Effect of Encapsulation in Cucurbit[10]uril

Eukaryotic Cell Toxicity and HSA Binding of [Ru(Me4phen)(bb7)]2+ and the Effect of Encapsulation in Cucurbit[10]uril

The toxicity (IC50) of a series of mononuclear ruthenium complexes containing bis[4(4′-methyl-2,2′-bipyridyl)]-1,n-alkane (bbn) as a tetradentate ligand against three eukaryotic cell lines—BHK (baby hamster kidney), Caco-2 (heterogeneous human epithelial colorectal adenocarcinoma) and Hep-G2 (liver...

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Bibliographic Details
Main Authors: Biyun Sun, Ian F. Musgrave, Anthony I. Day, Kirsten Heimann, F. Richard Keene, J. Grant Collins
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Chemistry
Subjects:
ruthenium complexes
cytotoxicity
HSA binding
cucurbit[10]uril
supramolecular chemistry
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00595/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00595/full

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