Phenotypes and gene expression profiles of <it>Saccharopolyspora erythraea </it>rifampicin-resistant (<it>rif</it>) mutants affected in erythromycin production

<p>Abstract</p> <p>Background</p> <p>There is evidence from previous works that bacterial secondary metabolism may be stimulated by genetic manipulation of RNA polymerase (RNAP). In this study we have used rifampicin selection as a strategy to genetically improve the er...

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Bibliographic Details
Main Authors: Bicciato Silvio, Corti Giorgio, Talà Adelfia, Ferrari Francesco, Tredici Salvatore M, Peano Clelia, Carata Elisabetta, De Bellis Gianluca, Alifano Pietro
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/8/1/18