Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction

<p>Abstract</p> <p>Background</p> <p>Previous studies have noted that drug targets appear to be associated with higher-degree or higher-centrality proteins in interaction networks. These studies explicitly or tacitly make choices of different source databases, data inte...

Full description

Bibliographic Details
Main Authors: Mora Antonio, Donaldson Ian M
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/294