Trapping para-Quinone Methide Intermediates with Ferrocene: Synthesis and Preliminary Biological Evaluation of New Phenol-Ferrocene Conjugates

Trapping para-Quinone Methide Intermediates with Ferrocene: Synthesis and Preliminary Biological Evaluation of New Phenol-Ferrocene Conjugates

The reaction of para-hydroxybenzyl alcohols with ferrocene in the presence of a catalytic amount of InCl3 provided ferrocenyl phenol derivatives, an interesting class of organometallic compounds with potential applications in medicinal chemistry. This transformation exhibited a reasonable substrate...

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Bibliographic Details
Main Authors: Silvia González-Pelayo, Enol López, Javier Borge, Noemí de-los-Santos-Álvarez, Luis A. López
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
ferrocene
phenol
para-quinone methides
cytotoxic activity
Online Access:http://www.mdpi.com/1420-3049/23/6/1335

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