Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma

Somatic mutation-associated T follicular helper cell elevation in lung adenocarcinoma

T follicular helper cells (Tfh) play crucial roles in the development of humoral immunity. In the B cell-rich germinal center of lymphoid organs, they select for high-affinity B cells and aid in their maturation. While Tfh have known roles in B cell malignancies and have prognostic value in some epi...

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Bibliographic Details
Main Authors: Kevin W Ng, Erin A Marshall, Katey SS Enfield, Spencer D Martin, Katy Milne, Michelle E Pewarchuk, Ninan Abraham, Wan L Lam
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:OncoImmunology
Subjects:
t follicular helper cell
tertiary lymphoid organ
lung adenocarcinoma
neoantigen
ct antigen
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1504728

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