Periapical bone response to bacterial lipopolysaccharide is shifted upon cyclooxygenase blockage

Abstract Objectives: Infection, inflammation and bone resorption are closely related events in apical periodontitis development. Therefore, we sought to investigate the role of cyclooxygenase (COX) in osteoclastogenesis and bone metabolism signaling in periapical bone tissue after bacterial lipopol...

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Bibliographic Details
Main Authors: Fernanda Regina Ribeiro-Santos, Geyson Galo da Silva, Igor Bassi Ferreira Petean, Maya Fernanda Manfrin Arnez, Léa Assed Bezerra da Silva, Lúcia Helena Faccioli, Francisco Wanderley Garcia Paula-Silva
Format: Article
Language:English
Published: University of São Paulo
Series:Journal of Applied Oral Science
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572019000100457&lng=en&tlng=en