Establishment and identification of a mouse model of Fscb/Cabyr double gene knockout

Establishment and identification of a mouse model of Fscb/Cabyr double gene knockout

Objective To construct a mouse model of targeted knockout of Fscb/Cabyr dual genes by using the CRISPR/Cas9 system, in order to found a basis for the study of the role of FSCB and CABYR protein complexe in sperm flagellum movement and capacitation. Methods The targeting sites for CRISPR/Cas9 system...

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Bibliographic Details
Main Authors: LI Zhongtai, LI Yanfeng, LIU Jinyi
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-10-01
Series:Di-san junyi daxue xuebao
Subjects:
gene knockout
sperm flagella
crispr / cas9 system
animal model
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202005029.htm

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