Influence of advanced age of maternal grandmothers on Down syndrome
<p>Abstract</p> <p>Background</p> <p>Down syndrome (DS) is the most common chromosomal anomaly associated with mental retardation. This is due to the occurrence of free trisomy 21 (92–95%), mosaic trisomy 21 (2–4%) and translocation (3–4%). Advanced maternal age is a we...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-01-01
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Series: | BMC Medical Genetics |
Online Access: | http://www.biomedcentral.com/1471-2350/7/4 |