Influence of advanced age of maternal grandmothers on Down syndrome

<p>Abstract</p> <p>Background</p> <p>Down syndrome (DS) is the most common chromosomal anomaly associated with mental retardation. This is due to the occurrence of free trisomy 21 (92–95%), mosaic trisomy 21 (2–4%) and translocation (3–4%). Advanced maternal age is a we...

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Bibliographic Details
Main Authors: Ramachandra Nallur B, Malini Suttur S
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/7/4