EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

Experimental allergic encephalomyelitis (EAE) in mice is characterized with changes in main lymphocyte populations and sub-populations. It was shown that tilorone normolizes the level of T- and B-lymphocytes, T/B ratio, and distribution into sub-populations at all studied terms of the disease. The a...

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Main Authors: Т. Ю. Степанова, Т. О. Філіпова, Б. М. Галкін
Format: Article
Language:English
Published: Odessa I. I. Mechnikov National University 2010-03-01
Series:Mìkrobìologìâ ì Bìotehnologìâ
Subjects:
експериментальний алергічний енцефаломієліт
тілорон
т- та в-лімфоцити
Online Access:http://mbt.onu.edu.ua/article/view/98566
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spelling doaj-1669461d694541588e9eac4b44f62a1d2021-01-27T09:12:35ZengOdessa I. I. Mechnikov National University Mìkrobìologìâ ì Bìotehnologìâ2076-05582307-46632010-03-0101(9)737910.18524/2307-4663.2010.1(9).9856698566EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITISТ. Ю. Степанова0Т. О. Філіпова1Б. М. Галкін2Одеський національний університет імені І. І. МечниковаОдеський національний університет імені І. І. МечниковаОдеський національний університет імені І. І. МечниковаExperimental allergic encephalomyelitis (EAE) in mice is characterized with changes in main lymphocyte populations and sub-populations. It was shown that tilorone normolizes the level of T- and B-lymphocytes, T/B ratio, and distribution into sub-populations at all studied terms of the disease. The activation of T-suppressors with tilorone fully implements an expexted therapeutic effect of this medicine at EAE.http://mbt.onu.edu.ua/article/view/98566експериментальний алергічний енцефаломієліттілоронт- та в-лімфоцити
collection DOAJ
language English
format Article
sources DOAJ
author Т. Ю. Степанова
Т. О. Філіпова
Б. М. Галкін
spellingShingle Т. Ю. Степанова
Т. О. Філіпова
Б. М. Галкін
EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
Mìkrobìologìâ ì Bìotehnologìâ
експериментальний алергічний енцефаломієліт
тілорон
т- та в-лімфоцити
author_facet Т. Ю. Степанова
Т. О. Філіпова
Б. М. Галкін
author_sort Т. Ю. Степанова
title EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
title_short EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
title_full EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
title_fullStr EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
title_full_unstemmed EFFECT OF TILORONE ON MAIN LYMPHOCYTE POPULATIONS AND SUB-POPULATIONS IN MICE WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
title_sort effect of tilorone on main lymphocyte populations and sub-populations in mice with experimental allergic encephalomyelitis
publisher Odessa I. I. Mechnikov National University
series Mìkrobìologìâ ì Bìotehnologìâ
issn 2076-0558
2307-4663
publishDate 2010-03-01
description Experimental allergic encephalomyelitis (EAE) in mice is characterized with changes in main lymphocyte populations and sub-populations. It was shown that tilorone normolizes the level of T- and B-lymphocytes, T/B ratio, and distribution into sub-populations at all studied terms of the disease. The activation of T-suppressors with tilorone fully implements an expexted therapeutic effect of this medicine at EAE.
topic експериментальний алергічний енцефаломієліт
тілорон
т- та в-лімфоцити
url http://mbt.onu.edu.ua/article/view/98566
work_keys_str_mv AT tûstepanova effectoftiloroneonmainlymphocytepopulationsandsubpopulationsinmicewithexperimentalallergicencephalomyelitis
AT tofílípova effectoftiloroneonmainlymphocytepopulationsandsubpopulationsinmicewithexperimentalallergicencephalomyelitis
AT bmgalkín effectoftiloroneonmainlymphocytepopulationsandsubpopulationsinmicewithexperimentalallergicencephalomyelitis
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